Underwriters' Acceleration Request

June 2, 2020

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549


Michael Clampitt

Jessica Livingston

Vanessa Robertson

David Burton



Applied Molecular Transport Inc.


Registration Statement on Form S-1 (File No. 333-238464)

Ladies and Gentlemen:

Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended, we wish to advise that between June 2, 2020 and the date hereof, approximately 1,600 copies of the Preliminary Prospectus dated June 1, 2020 were distributed to prospective underwriters, institutional investors and prospective dealers in connection with the above-captioned Registration Statement.

We wish to advise you that the participating underwriters have informed us that they have complied and will continue to comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

We hereby join in the request of the registrant that the effectiveness of the above-captioned Registration Statement, as amended, be accelerated to 4:00 p.m. Eastern Time, on Thursday, June 4, 2020, or as soon thereafter as practicable.

[Signature page follows]

Very truly yours,




As representatives of the Underwriters


By:   BofA Securities, Inc.
By:   /s/ Michael Liloia
  Name: Michael Liloia
  Title: Director


By:   Jefferies LLC
By:   /s/ Michael Brinkman
  Name: Michael Brinkman
  Title: Managing Director


By:   SVB Leerink LLC
By:   /s/ Murphy Gallagher
  Name: Murphy Gallagher
  Title: Managing Director